Reducing the global health impact of influenza requires a careful review of the history of the disease as well as an evaluation of where influenza infection may be going next. Overall, the 2015-2016 influenza season was moderate in terms of infection activity and clinical consequences. The prevalence of influenza infection and complications was lower than that of previous years.
There was a good match between the influenza strains chosen for the 2015-2016 vaccine and the strains that promoted influenza infection in that same period. Traditionally, the vast majority of influenza deaths occur among children who were not vaccinated. Half of the influenza deaths in 2015-2016 were among children without a high-risk underlying medical condition.